Enterprise Knowledge for AI

Roche
Semantic Hub

The enterprise knowledge hub that grounds AI agents in Roche-specific context — so they understand requests, cut hallucinations, and deliver outcomes that matter.

The Problem

Advanced AI tools are only as effective as the context they are given. As these technologies become more complex, the greatest hurdle is feeding them the rich, specialized knowledge they need to actually understand the business.

General AI lacks Roche context

AI tools have spread across every function — but they're trained on the public web, not Roche's data/metadata. They cannot reason over knowledge they have never seen.

No shared context leads to a lack of trust

Without a single source of Roche-specific meaning, every team tries to resolve the same problem — and AI keeps hallucinating, misinterpreting information, and returning results no one can rely on.

AI tools that require enterprise context

AI chatbots with users
AI for R&D
AI driven search
AI driven content generation

The Solution

One governed hub that turns scattered Roche knowledge into context every AI agent can use — so answers are grounded, not guessed.

Roche knowledge
Ontologies
Terminologies
Master Data
Reference Data
Business Metadata
Governed & linked
Roche
Semantic Hub
One semantically linked knowledge base
What AI agents get
Answers grounded in Roche context
Fewer hallucinations
One shared source of meaning
Faster, reusable across domains

The Value

Speed to market, proven capabilities, and a clear operational model that lets domains focus on outcomes rather than infrastructure.

62
Months
Speed to Market

Building a basic knowledge hub independently typically requires 6+ months across resource allocation, technical design, infrastructure setup, pipeline integration, and optimisation. By leveraging the shared Roche Semantic Hub, domains reduce this to approximately 2 months for any domain that can scale across multiple use cases.

Metadata Augmentation

Enrich missing fields in metadata catalogs such as the R&D Dataset Portal (RDP), improving data completeness and downstream AI accuracy.

Enhanced AI Search

Maps synonyms — e.g. RO5541267 / atezolizumab / Tecentriq — so AI retrieves experimental data regardless of which identifier a researcher uses.

Connectivity of Roche Semantic Hub

Links terminologies, ontologies, and master data across sources into one Knowledge Graph — so an agent can traverse from a compound to its targets, trials, and indications in a single query, instead of stitching together siloed systems.

Vision

Five guiding principles that shape how the Roche Semantic Hub is built, evolved, and measured.

01

Unify Enterprise Knowledge

Integrate Roche's terminologies, ontologies, reference and master data into one governed knowledge store.

02

Serve AI Agents On Demand

Expose that knowledge through services that power AI and Therapeutic Discovery across the enterprise.

03

Ship Real Use Cases First

Build for genuine business needs — proven outcomes over theoretical completeness.

04

Prove Outcomes With Data

Continuously evaluate agent performance to drive improvement and demonstrate clear ROI.

05

Connect Every Domain

Link the Hub to domain-specific systems for deeper, more accurate understanding of Roche workflows.

Architecture

Three layers work together: data Sources feed the Roche Semantic Hub, which exposes knowledge via MCP and GraphQL API to a rich Consumption Layer of AI tools and users.

Sources
RTiS
MRHub
GA
Global
Acronyms
Collibra *
More sources planned
Roche Semantic Hub
KG Knowledge Graph Core data with semantic mappings
Virtualization On-the-fly retrieval
GraphQL API
MCP
Fixed
Dynamic
Consumption Layer
Systems
AI Agents
Domain
Semantic Layers
End Users

* Collibra integration is planned. For a technical overview of the hybrid on-prem / cloud architecture, see the appendix slides in the original deck.

To find out more about sources integrated into the Roche Semantic Hub and available services, visit Graph Content and Services.

Ready to accelerate your domain?

Watch the narrated video walkthrough or reach out to the Roche Semantic Hub team to explore how the Roche Semantic Hub can reduce your time to production from 6 months to 2.

Watch Video Walkthrough